The entire lab had a fantastic time at the 2026 Joint Metabolism, Aging, Pathogenesis, Stress, and Small RNA (MAPSS) & Development, Gene Expression, and Cell Biology (DevCell) Meeting! 🪱

Claire gave an oral presentation highlighting the lab’s latest research and introduced Worm Integrated Explorer (WormIE), our new web tool developed by Sherlyn together with our informatics collaborator Ray Sinurat. Sherlyn, Manny, Nikita, Ruiling, and Helen also presented posters, making it a wonderful opportunity to share our work and connect with the C. elegans research community.

If you work with C. elegans, we’d love for you to give WormIE a try and let us know what you think!

Nikita Shiliaev’s first author paper on synaptic vesicle protein turnover is now published in Molecular Biology of the Cell ! Check it out here. The paper introduces the ARGO method, a genetically encoded, fluorescence microscopy approach to quantifying protein turnover, which we hope will be a useful tool for your research!

The whole lab enjoyed attending the Wisconsin Nathan Shock Center Symposium (WiNSC)! We had a great time catching up with colleagues, learning about exciting research, and sharing our own work, with Ruiling presenting a poster on behalf of the lab.

Congratulations to Serenity, Gabe, and Emma on their graduation! 🎓

We’re sad to say goodbye to Gabe and Emma but excited to see them begin the next chapter of their careers: Gabe as a Research Technologist I in the E Lab at the Medical College of Wisconsin and Emma as a Genetic Counseling Assistant at the UW Health Carbone Cancer Center. The good news is that Serenity isn’t going far—we’re thrilled she’ll be staying with us as our new lab manager! We couldn’t be prouder of all three and wish them continued success.

Congratulations to Helen on being awarded the Undergraduate Distinguished Research Fellowship! 🎉 This prestigious fellowship recognizes her outstanding research achievements and will support her continued work in the lab.

After several wonderful years with the lab, Sophie is embarking on an exciting new chapter as an Environmental Health Specialist with Rock County! We’re incredibly grateful for everything she has done as our lab manager and wish her all the best in her new role. Thank you, Sophie—you’ll always be part of the lab family!

Congratulations to Sophia on publishing her research! 🎉 Her work, completed as part of her undergraduate research in the lab, has now been published in PLOS ONE, an exciting milestone in her research journey. We’re incredibly proud of this achievement and look forward to seeing what she accomplishes next! 👏📖🔬

Read her article here!

Ruiling presented the lab’s latest research at the Cells, Science, Imaging (CSI) Meeting! Thank you to the CSI organizers for providing a great opportunity to share our work and connect with the research community.

The first of many: our lab’s first review article is now published in Cells! This review highlights how lysosomal function supports neuronal health during aging and how age-associated declines contribute to neuronal dysfunction.

You can read the article here.

Claire presented an oral talk at the American Society for Cell Biology (ASCB)’s Cell Bio 2025. We are grateful for the momentum built over the past year and excited for what lies ahead.